Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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First-aid measures

Following inhalation: Remove patient from exposure, keep warm and at rest. Administer oxygen if necessary. Apply artificial respiration if breathing has ceased or shows sign of failing. In the event of cardiac arrest apply external cardiac massage. Obtain immediate medical attention.
Following skin contact to the liquid or spray: Thaw affected areas with water. Remove contaminated clothing. Caution: clothing may adhere to the skin in the case of freeze burns. Wash skin with plenty of warm water. If irritation or blistering occur obtain medical attention.
Follwoing eye contact to the liquid or spray: Immediately irrigate with eyewash solution or clean water, holding the eyelids apart for at least 10 minutes. Obtain immediate medical attention.
Following ingestion of the liquid: unlikely route of exposure. Do not induce vomiting. Provided the patient is conscious, wash out mouth with water and give 200-300ml (half a pint) of water to drink. Obtain immediate medical attention.
Further medical treatment: Symptomatic treatment and supportive therapy as indicated. Adrenaline and similar sypathomimetic drugs should be avoided following exposure as cardiac arrhythimia may result wit possible subsequent cardiac arrest.




Fire-fighting measures

HFC 134a is not flammable in air under ambient conditions of temperature and pressure. Certain mixtures of HFC 134a and air when under pressure may be flammable. Mixtures of HFC 134a and air under pressure should be avoided. Certain mixtures of HFCs and chlorine may be flammable or reactive under certain conditions. Thermal decomposition will evolve very toxic and corrosive vapours of hydrogen fluoride. Containers may burst if overheated.
Extinguishing media: As appropriate for surrounding fire. Keep fire exposed containers cool by spraying with water.

Fire fighting protective equipment: A self contained breathing apparatus and full protective clothing must be worn in fire conditions.

Accidental release measures

Ensure suitable personal protection (including respiratory protection) during removal of spillages.

Provided it is safe to do isolate the source of the leak. Allow small spillages to evaporate provided there is adequate ventilation.
Large spillages: Ventilate the area. Contain spillages with sand, earth or any other suitable adsorbent material. Prevent liquid from entering drains, sewers, basements and workpits since the vapour may create a suffocating atmosphere.

Handling and storage

Handling
Avoid inhalation of high concentrations of vapours. Atmospheric concentrations should be controlled in compliance with the occupational exposure limit. The vapour is heavier than air, high concentrations may be produced at low levels where general ventilation is poor, in such cases provide adequate ventilation or wear suitable respiratory protective equipment with positive air supply.
Avoid contact between naked flames and hot surfaces as corrosive and very toxic decompostion products can be formed.
Avoid contact between the kiquid and skin and eyes.

Storage:
HFC‑134a (liquefied) is stored in cylinders and drums equipped with pressure relief valves. The cylinders should be kept in a clean, dry, well-ventilated area at temperatures preferably below 45°C. However in hot climates this temperature can be exceeded, and, as a result, drums and cylinders are tested at a reference temperature of 65°C. Storage vessels should be kept away from open flames, direct sunlight and all other sources of heat. Bulk installations are equipped with pressure relief systems, and storage temperatures are subject to the regulations of the territory.

Transport information

Land transport (ADR/RID)

UN number:
UN 3159
Proper shipping name and description:
1,1,1,2-TETRAFLUOROETHANE or REFRIGERANT GAS R 134a
Chemical name:
1,1,1,2-tetrafluoroethane
Language:
English
Class:
2 (divsion 2.2)
Classification code:
2A
Packaging group:
Not applicable
Labels:
No. 2.2, non-flammable, non-toxic gas
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Inland waterway transport (ADN(R))

UN number:
UN 3159
Proper shipping name and description:
1,1,1,2-TETRAFLUOROETHANE or REFRIGERANT GAS R 134a
Chemical name:
1,1,1,2-tetrafluoroethane
Language:
English
Class:
2 (division 2.2)
Classification code:
2A
Packaging group:
Not applicable
Labels:
No. 2.2, non-flammable, non-toxic gas,
Remarksopen allclose all

Marine transport (IMDG)

UN number:
UN 3159
Proper shipping name and description:
1,1,1,2-TETRAFLUOROETHANE or REFRIGERANT GAS R 134a
Chemical name:
1,1,1,2-tetrafluoroethane
Class:
2.2
Packaging group:
not applicable
EmS code:
F-C, S-V
Labels:
No. 2.2, non-flammable, non-toxic gas
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
UN 3159
Proper shipping name and description:
1,1,1,2-Tetrafluoroethane
Chemical name:
1,1,1,2-tetrafluoroethane
Class:
2.2
Packaging group:
not applicable
Labels:
2.2, non-flammable, non-toxic gas
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Wear suitable protective clothing, gloves, eye/face protection. Wear thermal insulating gloves when handling liquefied gases. In cases of insufficient ventilation, where exposure to high concentrations of vapour is possible, suitable respiratory protective equipment with positive air supply should be used.

The UK EH40 WEL is 1000ppm (4240 mg/m3) 8Hr TWA

Stability and reactivity

Certain mixtures of HFC 134a and chlorine may be flammable or reactive under certain conditions.
Incompatible materials: finely divided metals, magnesium and alloys containing more than 2% magnesium. Can react violently if in contact with alkali metals and alkaline earth metals - sodium potassium and barium.

Thermal decompositon or hydrolysis will produce hydrogen fluoride.

Disposal considerations

Best to recover or recycle. If this is not possible destruction is to be in an approved facility which is equipped to absorb and neutralise acid gases and other toxic processing products.