Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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First-aid measures

Inhalation: Remove patient from exposure, keep warm and at rest. Administer oxygen if necessary. Apply artificial respiration if breathing has ceased or shows signs of failing. In the event of cardiac arrest apply external cardiac massage. Obtain immediate medical attention.

Skin Contact: Thaw affected areas with water. Remove contaminated clothing. Caution: clothing may adhere to the skin in the case of freeze burns. After contact with skin, wash immediately with plenty of warm water. If irritation or blistering occur obtain medical attention.

Eye Contact: Immediately irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain immediate medical attention.

Ingestion: Unlikely route of exposure. Do not induce vomiting. Provided the patient is conscious, wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain immediate medical attention.

Further Medical Treatment: Symptomatic treatment and supportive therapy as indicated. Adrenaline and similar sympathomimetic drugs should be avoided following exposure
as cardiac arrhythmia may result with possible subsequent cardiac arrest.

Fire-fighting measures

General: HFC 134a is not flammable in air under ambient conditions of temperature and pressure. Certain mixtures of HFC 134a and air when under pressure may be flammable. Mixtures of HFC 134a and air under pressure should be avoided. Certain mixtures of HFCs and chlorine may be flammable or reactive under certain conditions.

Extinguishing media: As appropriate for surrounding fire. Keep fire exposed containers cool by spraying with water.

Special hazards arising from the substance or mixture: Thermal decomposition will evolve very toxic and corrosive vapours. (hydrogen fluoride )
Containers may burst if overheated.

Advice for firefighters: A self contained breathing apparatus and full protective clothing must be worn in fire conditions.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: Ensure suitable personal protection (including respiratory protection) during removal of spillages.

Environmental precautions: Prevent liquid from entering drains, sewers, basements and workpits since the vapour may create a suffocating atmosphere.

Methods and materials for containment and cleaning up: Provided it is safe to do so, isolate the source of the leak. Allow small spillages to evaporate provided there is adequate ventilation. Large spillages: Ventilate area. Contain spillages with sand, earth or any suitable adsorbent material. Prevent liquid from entering drains, sewers, basements and workpits since the vapour may create a suffocating atmosphere.

Handling and storage

Precautions for safe handling: Avoid inhalation of high concentrations of vapours. Atmospheric levels should be controlled in compliance with the occupational exposure limit.
Atmospheric concentrations well below the occupational exposure limit can be achieved by good occupational hygiene practice.
The vapour is heavier than air, high concentrations may be produced at low levels where general ventilation is poor, in such cases provide adequate ventilation or wear suitable respiratory protective equipment with positive air supply.
Avoid contact with naked flames and hot surfaces as corrosive and very toxic decomposition products can be formed.
Avoid contact between the liquid and skin and eyes.
Avoid venting to atmosphere.

Process Hazards: Liquid refrigerant transfers between refrigerant containers and to and from systems can result in static generation. Ensure adequate earthing.
Certain mixtures of HFCs and chlorine may be flammable or reactive under certain conditions. Care must be taken to mitigate the risk of developing high pressures in
systems caused by a temperature rise when liquid is trapped between closed valves or in cases where containers have been overfilled.

Conditions for safe storage, including any incompatibilities: Keep in a well ventilated place away from fire risk and avoid sources of heat such as electric or steam radiators.
Avoid storing near to the intake of air conditioning units, boiler units and open drains.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
3159
Shipping information
Proper shipping name and description:
1,1,1,2-Tetrafluoroethane
Chemical name:
1,1,1,2-Tetrafluoroethane
Language:
English
Labels:
2.2
SpecialProvisionsopen allclose all

Inland waterway transport (UN RTDG/ADN(R))

UN number:
3159
Shippingopen allclose all
Labels:
2.2
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

UN number:
3159
Shipping information
Proper shipping name and description:
1,1,1,2-Tetrafluoroethane
Chemical name:
1,1,1,2-Tetrafluoroethane
Labels:
2.2
Remarksopen allclose all

Air transport (UN RTDG/ICAO/IATA)

UN number:
3159
Shipping information
Proper shipping name and description:
1,1,1,2-Tetrafluoroethane
Chemical name:
1,1,1,2-Tetrafluoroethane
Labels:
2.2
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Appropriate engineering controls: Provide adequate ventilation. Atmospheric levels should be controlled in compliance with the occupational exposure limit.

Personal protection equipment: Wear suitable protective clothing and eye/face protection.

Respirators: In cases of insufficient ventilation, where exposure to high concentrations of vapour is possible, suitable respiratory protective equipment with positive air supply should be used.

Eye Protection: Wear protective eyewear (goggles, face shield, or safety glasses).

Gloves: Wear thermal insulating gloves when handling liquefied gases.

Occupational exposure limit:

1,1,1,2-Tetrafluoroethane (HFC 134a) 1000 ppm (8hr TWA); 4240 mg/m3 (8 hr TWA). UK HSE WEL

Stability and reactivity

Reactivity: See Possibility of hazardous reactions

Chemical stability: Stable under normal conditions.

Possibility of hazardous reactions: Certain mixtures of HFCs and chlorine may be flammable or reactive under certain conditions.

Incompatible materials: finely divided metals , magnesium and alloys containing more than 2% magnesium . Can react violently if in contact with alkali metals and alkaline earth metals - sodium , potassium , barium.

Conditions to avoid: Avoid high temperatures.

Incompatible materials: finely divided metals , alkali metals ( sodium , potassium ) , alkaline earth metals ( barium , magnesium ) , alloys containing more than 2% magnesium
Hazardous decomposition products: hydrogen fluoride by thermal decomposition and hydrolysis.

Disposal considerations

Waste treatment methods: Best to recover and recycle. If this is not possible, destruction is to be in an approved facility which is equipped to absorb and neutralise acid gases and other toxic processing products.

Regulatory Information: Disposal should be in accordance with local, state or national legislation.