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EC number: 256-032-2 | CAS number: 42978-66-5
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish: With high probability acutely toxic to fish.
Key study: BASF AG (1988, report no. 10F0158/885179). DIN 38412-15, Leuciscus idus:
- 96-h LC50 = 4.6 – 10 mg/L (nom.)
Long-term toxicity data to fish: no data available.
no data available. Information requirement waived based on the results of the chemical safety assessment (no PBT/vPvB; RCR < 1).
Short term toxicity to aquatic invertebrates:With high probability acutely harmful to aquatic invertebrates.
Key study: BASF AG (1988, report no. 1/0671/2/88-0671/88): EU method C.2, Daphnia magna:
48-h EC50 = 89 mg/L (nom.)
Long-term toxicity to aquatic invertebrates:no data available. Information requirement waived based on the results of the chemical safety assessment (no PBT/vPvB; RCR < 1).
Toxicity to aquatic algae and cyanobacteria: Acutely toxic to aquatic algae.
Key study: BASF AG (1988, report no. 88/0671): DIN 38412 p. 9, Desmodesmus subspicatus:
72-h ErC50 = 65.9 mg/L (nom.)
72-h ErC10 = 6.6 mg/L (nom.)
Toxicity to aquatic microorganisms: The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Weight-of-evidence - 30 -min EC 50 > 1000 mg/L:
TPGDA (CAS 42978-66-5): short-term respiration inhibition study (Robra), Pseudomona putida (BASF AG, 1988, rep.no.: 01/88/0671):
30 -min EC10 > 10000 mg/L (nom.), EC50 > 10000 mg/L (nom.)
Structurally similar substance CAS 57472-68-1: short-term respiration inhibition study according to OECD 209, domestic activated sludge (GLP; BASF AG, 2002, rep. no.: 02/0368/08/1)
30-min EC20 > 1000 mg/L (nom.)
Conclusion:Based on the available experimental data, TPGDA (CAS 42978-66--5) is considered to be acutely toxic to aquatic organisms.
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