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Short-term toxicity to fish

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Description of key information

LC50 for freshwater fish 96h= 325 mg/L

Key value for chemical safety assessment

LC50 for freshwater fish:
325 mg/L

Additional information

A single, good quality (non-GLP) fish acute toxicity study is available for p-toluenesulfonic acid (CAS No. 104-15-4). The 96 hr LC50 is 500 mg/L which is equivalent to 325 mg active ingredient/L based on the test substance being 65% p-toluenesulfonic acid in water.

The study was conducted in 1981 with a test substance with a 65% purity (in solution). The testing procedure was similar to OECD Guideline 203 except there was no analytical confirmation of the test concentration, and the test species was the Goldorfen which, while often used, is not a standard test species. The study was a 96 hour, static exposure to 10, 100 and 500 mg/L test substance. The test conditions were confirmed as valid. No mortality or behavior abnormalities were obsered at any of the exposure levels or in the controls.No toxicity was observed in the study. The 96 hr LC50 (and NOEC) are 500 mg/L which is equivalent to 325 mg active ingredient/L based on the test substance being 65% p-toluenesulfonic acid in water.