Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

According to the measured BCF the substance does not significantly accumulate in organisms.

Key value for chemical safety assessment

BCF (aquatic species):
3.9

Additional information

To determine the bioaccumulative potential of TEA to aquatic organisms, a study conducted according to the OECD test guideline 305 was performed. Cyprinus carpio was used as test species. The determined BCF in this study was < 3.9 at a concentration of 0.25 mg/l whereas at a concentration of 2.5 mg/l a BCF < 0.4 was measured (MITI 1992).

This experimental result is supported estimated BCFs from a variety of models. The highest BCF was calculated to be 3. In all cases of the following models, TEA was within the applicability domain:

- EPI Suite v4.11, BCFBAF v3.01: BCF = 3

- US EPA T.E.S.T. v4.1: BCF = 0.46

- VEGA Read-across v1.0.2: BCF = 0.68

- VEGA Meylan v1.0.2: BCF = 3

- VEGA CAESAR v 2.1.13: BCF = 3

- OASIS Catalogic v5.11.9.13 BCF base-line model v02.07: BCF = 9.2 without mitigating factors; BCF = 2.4 taking into account mitigating factors like water solubility, molecular size and metabolism. Water solubility had the highest effect on reducing the bioaccumulation potential.