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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The reported LC100 value of 30000 mg/L exceeds the water solubility of calcium fluoride.

Key value for chemical safety assessment

LC50 for freshwater fish:
30 000 mg/L

Additional information

Studies with calcium fluoride

The acute toxicity of calcium fluoride was investigated in Tinca vulgaris. The reported LC100 value of 30000 mg/L exceeds the water solubility of the test material (Simonin & Pierron, 1937). Loeb & Kelly (1963) investigated the toxicity of a large number of substances in the carp by oral administration (force feeding). No deaths occurred following the administration of a single oral dose of calcium fluoride to carp at a level equivalent to 324 -431 mg/kg bw. Calcium fluoride was found to be of low acute oral toxicity to the carp (Cyprinus carpio) under the conditions of this study.

Studies with other fluorides

A number of studies have been performed with the water-soluble salt, sodium fluoride. LC50 values of 107.5, 92.4, 118.5, 105.1, 64.1 ppm at 96, 120, 144, 168 and 192 h respectively are reported for rainbow tout (Camargo & Tarazona, 1991). The same authors report LC50 value for brown trout of 164.5, 135.6, 118.5, 105.1 and 97.5 ppm after 96, 120, 144, 168 and 192 h respectively. The EU RAR for hydrogen fluoride reports additional LC50 values of 299 mg/L (48h in Leuciscus idus); 51 mg/L in (96h in Onchorynkus mykiss) and 340 mg/L (96h in Gasterosteus aculeatus). The RIVM Integrated Criteria Document reports additional data, with LC50 values ranging from 128 -460 mg/L (Sloof et al,1988). The RIVM document also reports LC50 values of >100 mg/L (the limit of solubility) for sodium fluoride in seawater.