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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
GLP compliance:
yes
Specific details on test material used for the study:
Purity not specified but typically ca. 98.9 %
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Details on inoculum:
-Sludge sampling were made at the following 10 places in Japan.
- Time of sludge sampling: March, June, September, and December in every year
- City sewage: Returned sluqge of sewage plants were collected.
- Rivers, lake and sea: Surface water and surface soil which is in contact with atmosphere were collected.
-Mixing of fresh and old activated sludge 5 L of the filtrate of the supernatant of an activated sludge in the present use was mixed with 500 mL of the filtrate of the supernatant of a newly collected sludge respectively and the mixture was cultured at pH 7.0 +1.0
under the sufficient aeration
- Concentration of sludge: 30 mg/L

Duration of test (contact time):
14 d
Initial conc.:
100 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
a) Water Temperature: 24 - 26 °C
b) Inoculum: standardized activated sludge, 30 mg/L as suspended solid
c) Exposure Vessel Type: 300 mL culture bottle
d) Number of Replicate: 3
Reference substance:
aniline
Remarks:
validity: BOD beyond 40% and 60% at the 7th and 14th day respectively
Key result
Parameter:
% degradation (O2 consumption)
Value:
>= 92 - <= 100
Sampling time:
14 d
Parameter:
% degradation (TOC removal)
Value:
>= 86 - <= 87
Sampling time:
14 d
Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
2-Hydroxyethyl methacrylate was degraded 92-100% after 14 days.
Executive summary:

2-Hydroxyethyl methacrylate was tested in a readily biodegradability screening test acc. OECD 301C (MITI-test). The substance was degraded for 92 -100% after 14 days. Therefore it is concluded that 2-hydroxyethyl methacrylate is readily biodegradable.

Description of key information

In the key study, biodegradation of 2-hydroxyethyl methacrylate in the OECD 301C MITI test reached 92 to 100% based on BOD and 86 to 87% based on TOC removal after 14 days (CITI Japan, 1992).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:
freshwater

Additional information

Supporting studies reported 98% biodegradation in 21 days in an OECD 301 E test (Fresenius, 1988) , and 84 % biodegradation after 28 days in an OECD 301 D test (Röhm, 1993).