Registration Dossier
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EC number: 254-413-8 | CAS number: 39318-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No skin sensitization data of sufficient quality are available for tungsten blue oxide (target substance). However, skin sensitization data are available for tungsten trioxide (source substance), which will be used for read-across. Due to similar water solubility, in vitro bioaccessibility in synthetic sweat fluid simulating dermal exposure, and available toxicity data for the target and source substances, the resulting toxicity potential would also be expected to be similar, so read-across is appropriate between these substances. In addition, read-across is appropriate for this endpoint because the classification and labelling is the same for the source and target substances, the PBT/vPvB profile is the same, and the dose descriptors are, or are expected to be, sufficiently similar or more conservative for the target substance. For more details, refer to the attached description of the read-across approach.
Migrated from Short description of key information:
No skin sensitization data of sufficient quality are available for tungsten blue oxide. However, data are available for tungsten trioxide, which will be used for read-across. In a skin sensitization study conducted on guinea pigs and according to OECD 406, tungsten trioxide was deemed to be not sensitising.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
Migrated from Short description of key information:
Although no study data specifically evaluating the potential respiratory sensitisation effects are available, based on the lack of human case reports indicating that tungsten blue oxide is a respiratory sensitiser, as well as negative responses observed in both the skin sensitisation and skin irritation animal studies, tungsten blue oxide is not likely to be a respiratory sensitiser
Justification for classification or non-classification
No skin sensitization data of sufficient quality are available for tungsten blue oxide. However, a skin sensitization test of sufficient quality and tested in accordance with standard methodology was available for tungsten trioxide. The results of this study showed that tungsten trioxide did not cause skin sensitization in Guinea Pigs. Therefore, based on read-across, no classification is required for the skin sensitization endpoint for tungsten blue oxide. No respiratory sensitization study is available for tungsten blue oxide. Therefore, classification cannot be made due to lack of data. However, this endpoint is not required for REACH registration.
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