Registration Dossier
Registration Dossier
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EC number: 254-413-8 | CAS number: 39318-18-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003-05-13 to 2003-07-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Well documented, scientifically sound study that was conducted in accordance to GLP and OECD Guideline 423; limit test.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Tungsten oxide
- EC Number:
- 254-413-8
- EC Name:
- Tungsten oxide
- Cas Number:
- 39318-18-8
- Molecular formula:
- WOn (n=2.99 to 2.90)
- IUPAC Name:
- Tungsten oxide
- Details on test material:
- - Name of test material (as cited in study report): Tungsten oxide blue
- Molecular formula (if other than submission substance): WO
- Physical state: Blue to black powder
- Analytical purity: 99.9%
- Purity test date: 2003-04-15
- Stability under test conditions: 5 years
- Storage condition of test material: Ambient temperature
- Other: Solubility in water- 118 mg/L at 20 degrees C
- pH: 6.9
Constituent 1
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Remarks on result:
- other: No severe toxic effects were present after a single dose of 2000 mg/kg of the test substance.
Applicant's summary and conclusion
- Conclusions:
- No severe toxic effects of tungsten oxide were noted by signs in life and post mortem. No mortality occurred. An LD50 of > 2000 mg/kg body weight for rats was established for the test substance.
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