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EC number: 254-413-8 | CAS number: 39318-18-8
No aquatic invertebrate short-term toxicity data of sufficient quality are available for tungsten oxide (target substance). However, aquatic invertebrate short-term toxicity data are available for sodium tungstate (source substance), which will be used for reading across. Due to lower water solubility and lower toxicity for the target substance compared to the source substance, the resulting read across from the source substance to the target substance is appropriate as a conservative estimate of potential toxicity for this endpoint. In addition, read across is appropriate because the PBT/vPvB profile is the same, and the dose descriptors are, or are expected to be, lower for the source substance. For more details, refer to the read-across category approach included in the Category section of this IUCLID submission and/or as an Annex in the CSR.
No data were available for tungsten blue oxide for invertebrate toxicity; therefore, read-across to sodium tungstate was used for this endpoint. In a test using Daphnia and testing sodium tungstate the EC50 observed was found to be greater than the highest concentration tested (>163 mg sodium tungstate/L or approximately 96 mg W/L).
Due to similar or lower transformation/dissolution results for tungsten blue oxide (the target substance) than sodium tungstate (the source substance), the resulting toxicity potential would also be expected to be similar or lower, so read-across is appropriate. In addition, read-across is justified because the classification and labelling is the same or less severe for the target substance, and the PBT/vPvB profile is the same. Finally, the dose descriptors are, or are expected to be, sufficiently similar or higher for the target substance, and read-across to the source chemical is adequately protective. For more details, refer to the attached description of the read-across approach.
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