Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-684-8 | CAS number: 1344-00-9
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- other: Internal health surveillance
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only abstract available: Experts´statement
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
Test material
- Reference substance name:
- Silicic acid, aluminum sodium salt
- EC Number:
- 215-684-8
- EC Name:
- Silicic acid, aluminum sodium salt
- Cas Number:
- 1344-00-9
- Molecular formula:
- nSiO2*mAl2O3*zNa2O n = 2-4; m = 0.12-3.20; z = 0.11-4.5
- IUPAC Name:
- aluminium(3+) sodium bis(oxosilanebis(olate))
- Test material form:
- solid: nanoform, no surface treatment
- Remarks:
- crystalline-free
Constituent 1
Results and discussion
Any other information on results incl. tables
Approximately 20 years of cumulative experience in the production of Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS) has not produced a single case of suspected contact allergy (Evonik 2009). NAS like synthetic amorphous silica is known to result in drying and possibly cracking the skin. Following prolonged exposure, this was associated with eczematous skin changes.
The implementation of technical measures resulted in a steady reduction of exposure over years. Furthermore, strict personal skin protection, as well as skincare, succeeded in almost eliminating any case of silicate-related skin irritation.
Applicant's summary and conclusion
- Conclusions:
- no evidence of skin sensitising potential
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
