Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

With high probability the test substance is acutely not harmful to aquatic algae.

Key value for chemical safety assessment

Additional information

The toxicity of iso-butanol on the green algae Pseudokirchneriella subcapitata was investigated in a GLP guideline study according to OECD 201 [DOW, 2007]. The measured 72h EC50 value for growth rate was 1799 mg/L and the 72h NOEC was 53 mg/L iso-butanol. A non-GLP, 48-hour test with the green algae Scenedesmus subspicatus according to a national standard method (DIN 38412 L9), confirms the low toxicity of iso-butanol on aquatic algae [Kuehn & Pattard, 1990]. The evaluation of the endpoint growth rate revealed an EC50 (48h) of 2300 mg/L and a NOEC of approximately 900 mg/L (EC10).