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EC number: 246-910-3 | CAS number: 25376-45-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
Little or no biodegradation was observed in aerobic and anaerobic soils; the main pathway for soil disappearance of TDA was the formation of covalent bonds with organic matter.
Key value for chemical safety assessment
Additional information
Available Soil Biodegradation Data
Experimental results are available form studies quoted by reliability (2). Those studies are well-documented although no guideline was followed. Using radiolabelled TDA, the biodegradation of both isomers were followed in aerobic or anaerobic conditions.
Degradation in Aerobic Conditions
Microbial degradation of both 2,4-TDA and 2,6-TDA using radiolabelled materials was investigated by Cowen et al (1996). Biodegradation of both isomers started immediately after mixing with the soil. Based on 14CO2 measurements, the calculated percentage of biodegradation are:
2,4 -TDA: 1.9% after 3d, 4.0% after 7d, 7.9% after 14d, 10.8% after 28d, 14.8% after 56d
2,6 -TDA: 2.7% after 3d, 6.2% after 7d, 11.1% after 14d, 14.2% after 28d, 18.1 % after 56d
During the latter period, the degradation rates indicate that biodegradation slowed down after TDA had formed covalent bounds to humic substances.
Under the conditions of the test, degradation products were not identified and it was not possible to calculate a half-life (DT50) for TDA in soil. In conclusion, TDA is covalently bound to organic matter and is expected to degrade almost similar to the humic acids themselves.
Degradation in Anaerobic Conditions
Microbial degradation of both 2,4-TDA and 2,6-TDA under anaerobic conditions were investigated by Cowen et al (1996) and by West and Davis (2002).
Under anaerobic conditions, no 14CH4 or 14CO2 was recovered after 73 days of incubation (Cowen et al, 1996).West and Davis (2002) reported experimental results of the biodegratation of 2,4- and 2,6-TDA in anaerobic soils under a wide range of redox conditions. Very limited biodegradation of 14C-TDA was observed in the sand soil under anaerobic, denitrifying conditions. The maximum yield of 14CO2 was detected after 1 year and was equivalent to 1.3% of the applied 14C-TDA.
Conclusion
-Little or no biodegradation was observed in aerobic and anaerobic soils,
-Consequently no DT50 was calculated for both 2,4 -TDA and 2,6 -TDA,
-Due to bonding to organic matter, biodegradation of TDA is expected to occur in combinaiton with humic acids.
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