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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Description of key information

For the dissociation constant determination at 20 °C only a SPARC Online Calculation from 2008 is available. Most data given are referred to an ambient temperature of 25 °C.

Key value for chemical safety assessment

pKa at 20°C:

Additional information

According to Beilstein (2006), monomethylamine has a pKa value of 10.76 (mean of 2 values) at 25 °C and a pKb value of 3.33 (mean of 7 values) at the same temperature. A pKa value of 10.66 at 25 °C is reported for monomethylamine according to Weast (2006). A similar value was indicated by Dean (1987), who reported a pKa of 10.62 at 25 °C. Additionally dissociation constants are estimated by the SPARC Online Calculator (2008) with the result of 10.657 at 25 °C, and 10.787 at 20 °C.