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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
other: Review
Adequacy of study:
supporting study
Reliability:
other: Review

Data source

Reference
Reference Type:
review article or handbook
Title:
Hydrazin, Hydrahzinhydrat und Hydrazinsulfat, BUA Stoffbericht No. 205
Author:
BUA (Beratergremium umweltrelevanter Altstoffe)
Year:
1996
Bibliographic source:
S. Hirzel Wissenschaftliche Verlagsgesellschaft

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
acute toxicity: oral
Principles of method if other than guideline:
poisoning incidents

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydrazine
EC Number:
206-114-9
EC Name:
Hydrazine
Cas Number:
302-01-2
Molecular formula:
H4N2
IUPAC Name:
hydrazine
Details on test material:
no further data

Method

Type of population:
occupational
Subjects:
poisoning incidents
Ethical approval:
not applicable
Route of exposure:
other: different routes
Reason of exposure:
accidental
Exposure assessment:
not specified
Examinations:
poisoning incidents
Medical treatment:
no data

Results and discussion

Clinical signs:
acute poisoning : vomiting, depression of central nervous system, liver and kidney damage and after inhaltaion pulmonary edema
Results of examinations:
A clear correlation between symptoms and exposure level is not given:
Effectivity of medical treatment:
no data
Outcome of incidence:
In man, acute poisoning with hydrazine causes vomiting, depression of central nervous system, liver and kidney damage and after inhaltaion pulmonary edema.

Applicant's summary and conclusion