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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
Laser particle sizer Malvern with unit dry Scirocco 2000
GLP compliance:
not specified
Type of method:
sieving
Type of distribution:
counted distribution
Percentile:
D50
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
No.:
#1
Size:
< 100 µm
Distribution:
ca. 80 %
Conclusions:
Particle size distribution indicates substance is an inhalation risk (a significant proportion of the particles are present at < 100 µm). This study is considered to be scientifically justified for use as a key study.

Description of key information

Particle size distribution data conducted to an acceptable in-house method have been supplied.

Additional information

Particle size distribution indicates substance is an inhalation risk (a significant proportion of the particles are present at < 100 µm).