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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-11-09 to 2010-02-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to OECD 105 test guideline, and in compliance with GLP.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
0.042 g/L
Temp.:
20 °C
pH:
4 - 4.1
Remarks on result:
other: Loading rate of 10 g/l and unadjusted pH
Details on results:
The mean water solubility of the test substance was 4.22 x 10-2 g/l, and the Range of all samples of Distilled Tall Oil is 4.68 x 10-3 to 4.23 x 10-2 g/l at 20 ± 0.5 °C.

Results

Preliminary test

The preliminary estimate of water solubility was dependent on loading rate. The results are shown in the following table:

Sample

Number

Nominal

Loading Rate (g/l)

Concentration (TOC) (g/l)

1

0.1

1.05 x 10-3

2

1.0

8.81 x 10-3

3

5.0

3.27 x 10-2

Definitive test

The concentration (g/l) of total organic carbon (TOC) in the sample solutions is shown in the following table:

Sample Number

Time Shaken at

~ 30ºC (hours)

Time Equilibrated at 20ºC (hours)

Concentration (TOC) (g/l)

Solution pH

Blank Matrix

-

-

<LOQ*

-

1

24

24

4.21 x 10-2

4.0

2

48

24

8.89 x 10-2†

4.0

3

72

24

4.23 x 10-2

4.1

4

72

24

9.75 x 10-3

5.6

5

72

24

4.68 x 10-3

5.2

6

72

24

6.20 x 10-3

6.0

Mean concentration of samples 1 and 3:  4.22 x 10-2 g/l at 20.0 ± 0.5ºC

Range of all samples:                                  4.68 x 10-3 to 4.23 x 10-2 g/l



*1.00 mg/l is the LOQ of the instrument.

†Excluded from the mean calculation and range, as it appears that the sample may not have been cleaned up sufficiently, compared to samples 1 and 3, hence the high result.

Conclusions:
Interpretation of results: slightly soluble (0.1-100 mg/L)

A water solubility value of 4.22 x 10-2 g/L at 20 ± 0.5°C was determined in a reliable study conducted according to OECD 105, and in compliance with GLP.

Description of key information

Water solubility: 4.22 x 10-2 g/L at 20°C, pH 4 - 4.1 (OECD 105).

Key value for chemical safety assessment

Water solubility:
0.042 g/L
at the temperature of:
20 °C

Additional information

Water solubility has been determined in a GLP study for the test substance using a method in accordance to OECD 105. DTO has a water solubility of 4.22 x 10-2g/L at 20°C, pH 4 - 4.1. The data is most recent, considered reliable and has been selected as key study. The result sums the contribution of all constituents.

In other supporting studies, a water solubility of 9 mg/L is also reported for the test substance in its entirety as a complex substance using the same method as stated above. The water solubility of samples of DTO with resin acid contents of 10 and 40% has been determined in accordance with OECD 105, respective values of 8.4 mg/L and 8.7 mg/L have been determined for the samples at 20°C.

The test substance is considered slightly soluble.