Tall oil

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-11-09 to 2010-02-26

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted according to OECD 105 test guideline, and in compliance with GLP.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

0.042 g/L

Temp.:

20 °C

pH:

4 - 4.1

Remarks on result:

other: Loading rate of 10 g/l and unadjusted pH

Details on results:

The mean water solubility of the test substance was 4.22 x 10-2 g/l, and the Range of all samples of Distilled Tall Oil is 4.68 x 10-3 to 4.23 x 10-2 g/l at 20 ± 0.5 °C.

Results

Preliminary test

The preliminary estimate of water solubility was dependent on loading rate. The results are shown in the following table:

Sample Number	Nominal Loading Rate (g/l)	Concentration (TOC) (g/l)
1	0.1	1.05 x 10^-3
2	1.0	8.81 x 10^-3
3	5.0	3.27 x 10^-2

Definitive test

The concentration (g/l) of total organic carbon (TOC) in the sample solutions is shown in the following table:

Sample Number	Time Shaken at ~ 30ºC (hours)	Time Equilibrated at 20ºC (hours)	Concentration (TOC) (g/l)	Solution pH
Blank Matrix	-	-	<LOQ*	-
1	24	24	4.21 x 10^-2	4.0
2	48	24	8.89 x 10^-2†	4.0
3	72	24	4.23 x 10^-2	4.1
4	72	24	9.75 x 10^-3	5.6
5	72	24	4.68 x 10^-3	5.2
6	72	24	6.20 x 10^-3	6.0

Mean concentration of samples 1 and 3:  4.22 x 10^-2 g/l at 20.0 ± 0.5ºC

Range of all samples:                                  4.68 x 10^-3 to 4.23 x 10^-2 g/l

*1.00 mg/l is the LOQ of the instrument.

†Excluded from the mean calculation and range, as it appears that the sample may not have been cleaned up sufficiently, compared to samples 1 and 3, hence the high result.

Conclusions:

Interpretation of results: slightly soluble (0.1-100 mg/L)

A water solubility value of 4.22 x 10-2 g/L at 20 ± 0.5°C was determined in a reliable study conducted according to OECD 105, and in compliance with GLP.

Description of key information

Water solubility: 4.22 x 10-2 g/L at 20°C, pH 4 - 4.1 (OECD 105).

Key value for chemical safety assessment

Water solubility:

0.042 g/L

at the temperature of:

20 °C

Additional information

Water solubility has been determined in a GLP study for the test substance using a method in accordance to OECD 105. DTO has a water solubility of 4.22 x 10^-2g/L at 20°C, pH 4 - 4.1. The data is most recent, considered reliable and has been selected as key study. The result sums the contribution of all constituents.

In other supporting studies, a water solubility of 9 mg/L is also reported for the test substance in its entirety as a complex substance using the same method as stated above. The water solubility of samples of DTO with resin acid contents of 10 and 40% has been determined in accordance with OECD 105, respective values of 8.4 mg/L and 8.7 mg/L have been determined for the samples at 20°C.

The test substance is considered slightly soluble.