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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information


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Administrative data

Description of key information

In a publication (Cheung, 1984) effects of the testsubstance on fagocytosis of immunocomplexes by neutrophils was investigated. It was found that the test substance significantly reduces chemiluminisence, which is considered a representative for the strength of the fagocytosis, compared to the chemiluminisence found with untreated control cells.  

Key value for chemical safety assessment

Additional information

The reference may discuss effects of the test substance on the non-specific part of immune system (fagocytosis), but is considered not sufficient to allow any conclusions.

Justification for classification or non-classification

Aggregated human gamma globulin (AHG) -induced chemiluminescence (CL) was suppressed in the presence of the test substance.