Registration Dossier
Registration Dossier
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EC number: 200-875-0 | CAS number: 75-50-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 28 mg/L
Additional information
The acute toxicity of trimethylamine (CAS 75-50-3) to aquatic invertebrates was studied in a GLP-guideline study following OECD 202. The test was performed under static conditions, using D. magna as test organism. The nominal test concentrations were analytically verified. The study was performed by the Ministry of the Environment (MOE of Japan) in 2011. The 48 -h EC50 for mobility was determined to be 28 mg/L (nominal). This value was selected as key data.
Supporting experimental data are available from an non-GLP guideline study, performed according to EU Directive 79/831/EEC, Annex V, part C without analytical monitoring (BASF AG, 1988). D. magna was used as test organism. Based on nominal test concentrations, the 48 -h EC50 for mobility was determined to be 139.95 mg/L.
In conclusion, the substance is assessed to be with high probability acutely not harmful to aquatic invertebrates.
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