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Ecotoxicological information

Long-term toxicity to fish

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Toxicity to fish has been investigated in 14 day test according to OECD Test Guideline No. 204. It is recognised that the duration of the OECD TG 204 test is shorter than that currently accepted for investigating long-term toxicity in fish. Waiving of repeat or additional testing is proposed based both on the lack of effects seen in the 14 -day fish study and chronic Daphnia reproduction studies together with considerations regarding adequate justification for the use of vertebrate species for experimental purposes.