Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 273-728-1 | CAS number: 69012-28-8 By-product of the manufacture of ferromanganese alloy containing primarily oxides of aluminum, manganese and silicon.
Table 1: Disintegrations per Minute, Disintegrations per Minute/Node and Stimulation Index.
Concentration (% w/w) in dimethyl formamide
dpm = disintegrations per minute
a = disintegrations per minute/node obtained by dividing the disintegrations per minute value by 8 (total number of lymph nodes)
b = Stimulation Index of 3.0 or greater indicates a positive result
na = not applicable
During the preliminary screening test, no signs of systemic toxicity were observed. In the main test, no deaths occurred and no signs of systemic toxicity were noted in the test or control animals.
The skin sensitisation potential of the test material was investigated in a study which was conducted under GLP conditions and in accordance with the standardised guidelines OECD 429 and EU Method B.42.
Under the conditions of the study the test material was concluded to be a non sensitiser.
Since the study was conducted with silicomanganese slag, rather than with the registered substance itself, it has been assigned a reliability score of 2 in line with the criteria of Klimisch (1997). Use of data generated with silicomanganese slag, to address information requirements of ferromanganese slag, is considered to be justified on the basis of the similar compositions of the two substances. Both substances are UVCB substances, containing metallic oxides; each substance is obtained as a by-product in the manufacture of SiMn and FeMn alloy, respectively.
In accordance with the criteria for classification as defined in Annex I, Regulation (EC) No. 1272/2008, the substance does not require classification with respect to sensitisation.
In accordance with the criteria for classification as defined in Annex VI, Directive 67/548/EEC (DSD), the substance does not require classification with respect to sensitisation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again