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EC number: 700-195-9 | CAS number: 223398-24-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- [TN]Gro 266[/TN][SPEC][/SPEC][AM]99%[/AM]
- IUPAC Name:
- [TN]Gro 266[/TN][SPEC][/SPEC][AM]99%[/AM]
- Details on test material:
- TEST ITEM: Gro 266
Batch number: Gro-RN-9963-191
CAS-No.: 223398-24-1
Content: > 99 weight %
Chemical name: 4-Acetyl-1-methylpyridinium-p-toluolsulfonate
Appearance: White-beige powder
Sum formula: C8H10NO x C7H7SO3
Molecular weight: 307.37 g/mol
Water solubility: Approx. 500 g/L
pH value: Approx. 3.8 (200 g/L)
Expiry date: 2014-04-01
Recommended storage: Frigid, dark
Storage at test facility: 6 ± 2 °C, protected from moisture and light
Retention of test item: At least 1 g has been retained.
ldentification parameter at test facility: Name, batch number, state, consistency and colour
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- LOEC
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: not applicable
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: not applicable
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Any other information on results incl. tables
ln the acute immobilization test with Daphnia magna (STRAUS) the effects of the limit
concentration 100 mg/L of the test item Gro 266 (batch number: Gro-RN-9963-191) were
determined according to OECD 202 (2004). The limit test was conducted under static conditions
over a period of 48 hours from 2009-09-16 to 2009-09-18 at Dr. U. Noack-Laboratorien,
Käthe-Paulus-Str. 1, D-31 157 Sarstedt, Germany.
20 test organisms were exposed to the limit concentration and the control. The limit
concentration and the control were analysed via HPLC in the fresh media (0 hours) and in the
old media (48 hours). Details of the analytical method are given in part 9. The recoveries of the
test item in the limit concentration were 102 % of the nominal value in the fresh media at test
start (0 hours) and 100 % of the nominal value in the old media at test end (48 hours). All effect
values given are based on the nominal test item concentration (Table 1). Water quality
parameters (pH-value and dissolved oxygen concentration), measured at 0 and 48 hours, were
determined to be within the acceptable limits. The validity criteria of the test guideline were
fulfilled.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- At the limit concentration of 100 mg/L of the test item Gro 266, corresponding to a mean
measured concentration of 101 mg/L, no effect was observed.
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