Registration Dossier

Administrative data

Endpoint:
nanomaterial aspect ratio/shape
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Principles of method if other than guideline:
Guidelines from NanoDefine are applied:
Method selection according to Gaillard et al., Nanoscale Adv., 2019, 1, 781
TEM image evaluation according to Verleysen et al., Materials 2019, 12, 2274; doi:10.3390/ma12142274
GLP compliance:
no
Type of method:
transmission electron microscopy
Details on methods and data evaluation:
Sample Preparation:
A suspension in ethanol was dispersed between two object slides and applied on a TEM grid

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: nanoform, no surface treatment

Data gathering

Instruments:
TEM: Thermo-Fisher Talos F200i 200kV
Calibration:
every 12 months with Mag*i*Cal sample
Reproducibility:
systematic error +/-3%

Results and discussion

Shape description
Key result
Shape:
other: mixtures of particles with different shapes
Percentage:
50 %
Remarks on result:
other: The material is assigned to the “MULTIMODAL” shape category.
Aspect ratio
Key result
Remarks on result:
other: D50= 2,2:1

Applicant's summary and conclusion

Conclusions:
The material is assigned to the “MULTIMODAL” shape category and the particles have a median aspect ratio of 2,2:1.