Registration Dossier

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2011

Materials and methods

Principles of method if other than guideline:
The solution was measured by UV/VIS.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: nanoform

Results and discussion

Test substance stable:
no
Transformation products:
not measured

Any other information on results incl. tables

Solubility and stability of the test item:

test - solvent

solubility

measured byUV/VIS

dimethylsulfoxide(DMSO)

soluble

stable for one week

dimethylformamide(DMF)

soluble

stable for one week

N-pyrrolidone(NMP)

soluble

not stable

methanol

low solubility

not stable

acetonitrile

very low solubility

not stable

ethanol

very low solubility

not stable

acetone

not soluble

1,4-dioxane

not soluble

Applicant's summary and conclusion