Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
Deviations:
no
Principles of method if other than guideline:
The test substance is weighed into a mineral medium with a aquatic mixed population of microorganisms inoculated and 28 days incubated under aerobic conditions in the dark at 20 ± 1 ° C. Of the biodegradation of the test substance during this time with the help a respirometer, which records the oxygen consumption, determined.
GLP compliance:
yes
Specific details on test material used for the study:
- Batch no.: H 1431725
- Product no.: 418 048 01
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
- Type: aquatic mixed population of microorganisms (activated sludge)
- Source: Laboratory activated sludge plant, which is operated by municipal wastewater (Wupperverband)
- Preperation: none
Duration of test (contact time):
28 d
Initial conc.:
100 mg/L
Based on:
test mat.
Reference substance:
aniline
Parameter:
% degradation (O2 consumption)
Value:
0
Sampling time:
28 d
Details on results:
The calculation of the theoretical oxygen demand was made by ThOD NH3; i.e. assuming that in the experimental approaches there is no nitrification.
Results with reference substance:
In parallel experiments with the reference substance aniline a reduction of 95% was achieved after 28 days.
Validity criteria fulfilled:
not applicable
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
Under test conditions 0% degradation of N-(1,3-benzothiazol-2-ylsulfanyl)-2-methylpropan-2-amine was observed within 28 days. The substance has to be classified as not readily biodegradable.
Executive summary:

Under test conditions 0% degradation of N-(1,3-benzothiazol-2-ylsulfanyl)-2-methylpropan-2-amine was observed within 28 days. The substance has to be classified as not readily biodegradable.

Description of key information

Under test conditions 0 % degradation of TBBS was observed within 28 days; and hence the substance has to be classified as not readily biodegradable. The hydrolysis products of TBBS, such as MBT and tert-butylamine, are also reported as not biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information