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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982

Materials and methods

Type of study / information:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
other:Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)

Test material

Constituent 1
Chemical structure
Reference substance name:
Di(benzothiazol-2-yl) disulphide
EC Number:
204-424-9
EC Name:
Di(benzothiazol-2-yl) disulphide
Cas Number:
120-78-5
Molecular formula:
C14H8N2S4
IUPAC Name:
di(benzothiazol-2-yl) disulphide
Details on test material:
SH-82-009, 2,2'-dithio-bis-benzothiazole, test substance 70% in petrolatum

Method

Details on study design:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)

Results and discussion

Results:
no primary skin irritating effects observed in 0/53 volunteers

Any other information on results incl. tables

A repeated insult patch test gave no indication of skin irritation after repeated dermal application

Applicant's summary and conclusion