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Diss Factsheets
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EC number: 202-627-7 | CAS number: 98-01-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- other: health surveillance
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
- Study type:
- medical monitoring
- Endpoint addressed:
- skin irritation / corrosion
- repeated dose toxicity: inhalation
- Principles of method if other than guideline:
- Regular medical examinations
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-furaldehyde
- EC Number:
- 202-627-7
- EC Name:
- 2-furaldehyde
- Cas Number:
- 98-01-1
- Molecular formula:
- C5H4O2
- IUPAC Name:
- 2-furaldehyde
- Reference substance name:
- Furfuryl alcohol
- EC Number:
- 202-626-1
- EC Name:
- Furfuryl alcohol
- Cas Number:
- 98-00-0
- Molecular formula:
- C5H6O2
- IUPAC Name:
- 2-furylmethanol
Constituent 1
Constituent 2
Method
- Type of population:
- occupational
- Ethical approval:
- not specified
- Details on study design:
- Medical centre Sevnica, Slovenia performed regular medical examinations of Jugotanin employees from 1979 to 1989. Examined employees also included those exposed to furfural. The results of examinations performed on seven employees that were followed for ten years. The emphasis of preventive medical examinations was on personal history, precise physical examination and laboratory examinations.
Employees were born between 1942 and 1964. They were healthy and capable for work at the time of beginning their employment.
The examined employees had their spirometric, ECG and blood pressure parameters in the framework of reference values.
Results and discussion
- Results:
- During preventive health examinations, none of the employees complained about any problems that would be related to work burdens and noxious aspects of their jobs.
There were no fundamental deviations in physical status. None of the employees had any skin changes that would be a consequence of daily contact with chemicals.
Laboratory examinations did not show any pathologic deviations (spirometric, ECG, and blood pressure parameters) and the liver tests were in the limits of reference values.
Applicant's summary and conclusion
- Conclusions:
- None of the examined employees was diagnosed with health damages that would be related to furfural exposure.
- Executive summary:
Medical centre Sevnica, Slovenia performed regular medical examinations of Jugotanin employees from 1979 to 1989. Examined employees also included those exposed to furfural. The results of examinations performed on seven employees that were followed for ten years are in the appendix. The emphasis of preventive medical examinations was on personal history, precise physical examination and laboratory examinations.
Employees were born between 1942 and 1964. They were healthy and capable for work at the time of beginning their employment. During preventive health examinations, none of the employees complained about any problems that would be related to work burdens and noxious aspects of their jobs.
There were no fundamental deviations in physical status. None of the employees had any skin changes that would be a consequence of daily contact with chemicals. Breathing functions and cardiovascular systems of all the examinees were without pathological deviations. There were no peculiarities in any of the body organ systems as well.
One of the employees was diagnosed with Duyputren's contracture, two of the employees were suspected of excessive alcohol consumption which, however, was not confirmed with laboratory tests.
The examined employees had their spirometric, ECG, and blood pressure parameters in the framework of reference values.
Laboratory examinations did not show any pathologic deviations, and the liver tests were in the limits of reference values.
None of the examined employees was diagnosed with health damages that would be related to furfural exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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