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EC number: 295-440-5 | CAS number: 92045-58-4 A complex combination of hydrocarbons obtained by distillation of a gasoline which has been catalytically isomerized. It consists predominantly of hexane isomers boiling in the range of approximately 60°C to 66°C (140°F to 151°F).
Light catalytically cracked naphtha was administered once daily to pregnant rats on gestation days 0-19 via dermal application at doses of 30, 125, and 500 mg/kg to assess for developmental toxicity. Maternal parameters (food consumption, body weight gain, serum chemistry) were monitored throughout gestation and were not adversely affected by treatment. No adverse effects were observed on eproductive parameters (number of implants, resporptions, or viable fetuses) or on fetal parameters (body weight or crown:rump length). No evidence of teratogenicity was observed in fetues from pregant dams exposed to the test material. Based on the study results, the maternal NOAEL and the teratogenicity NOAEL were greater than 500mg/kg. These findings do not warrant the classification of light catalytically cracked naphtha as a developmental hazard under Regulation (EC) 1272/2008 on classification, labeling, and packaging of substances and mixtures (CLP) or under the Directive 67/518/EEC for dangerous substances and Directive 1999/45/EC for preparations.
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