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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

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Description of key information

A measured BCF is not available for alkenes C24 - 28. Log BCFs have been calculated using a QSAR for icos-2-ene and docos-2-ene. Calculated log BCFs are 1.6 - 2.1.

Key value for chemical safety assessment

Additional information

A measured BCF is not available for alkenes C24 -28. Based on read across the measured log Kow is >3, so the bioaccumulation endpoint cannot be waived. However, ECHA's Guidance on Information Requirements and Chemical Safety Assessment R7c Endpoint Specific Guidance (2008) indicates that before commissioning a new vertebrate test alternative sources of data on the bioaccumulation potential of a chemical should used.

Non-polar substances have been shown to have a linear relationship between log Kow and BCF in the log Kow range 1 - 6. However, at log Kow >6 a decreasing relationship is observed. Several QSARs have been developed that calculate the BCFs of non-polar, hydrophobic compounds on the basis of their log Kow (e.g. Connell and Hawker, 1988; USEPA, 2008). Icos-2-ene and docos-2-ene fall within the applicability domain of the USEPA QSAR, but slightly outside that of Connell and Hawker. The calculated log BCFs range from 1.6 - 2.1.

The log Kow of icos-2-ene and docos-2-ene have been calculated in KOWWIN (log Kows 9.95 and 10.93 respectively) and SPARC (log Kows 11.68 and 12.85 respectively). ECHA's guidance on information requirements and chemical safety assessment - Part C: PBT assessment (2008) states that the aquatic BCF of a substance is probably lower than 2000 l/kg if the calculated log Kow is higher than 10. As none of the log Kow models have experimental data in this log Kow range the reliability of modelled log Kow values >10 is not known. However, as both models indicate a log Kow >10 we can conclude that icos-2-ene, docos-2-ene and any substance with a higher carbon number is unlikely to bioaccumulate.

Taken together, this information indicates that alkenes C24 - 28 is not expected to bioaccumulate or pose a risk of secondary poisoning.