Registration Dossier
Registration Dossier
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EC number: 201-550-6 | CAS number: 84-66-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Algal growth inhibition: EC50 = 45 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 45 mg/L
- EC10 or NOEC for freshwater algae:
- 9 mg/L
Additional information
Toxicity to aquatic algae has been investigated in accordance with DIN methods. The 72 hour EC50, based on biomass, was 23 mg/L and, based on growth rate, was 45 mg/L. A second study, following EPA test methods and with the exposure period extended to 8 days, determined an EC50, based on cell numbers, of 30.3 mg/L.
In accordance with ECHA guidance oninformation requirements and chemical safety assessment,Chapter R.7b: Endpoint specific guidance, theErC50 endpoint is used in DNEL derivation. This is because use of values based on biomass cannot be applied to an analysis of results from a system in exponential growth without logarithmic transformation.
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