Registration Dossier
Registration Dossier
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EC number: 201-557-4 | CAS number: 84-74-2
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
As no more information is available on the effects of DBP on higher organisms other than laboratory mammals, the overall oral LOAEL of 52 mg/kg bw (see Section Toxicity for reproduction) will be used for the derivation of the PNEC for predators.
Key value for chemical safety assessment
Additional information
According to EU RAR for DBP, 2004 there are some tewsts with birds such a study by Peakall, 1974, who examined the effects of a diet of 10 mg DBP/kg on egg shell thickness, breaking strength, permeability and shell structure of ring dove (Streptophelia risoria) eggs in a 3-week experiment and egg shell thickness was found to be decreased (10%), whereas the water permeability increased (23%). A 15% decrease in shell thickness is considered significant for reproductive effects. Rapid recovery occurred upon cessation of exposure. The second was provided by Korhonen et al., 1983, where an ED50 of 33 μmol (9.19 mg) per egg was calculated for DBP in a chicken embryo toxicity study.
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