Registration Dossier

Administrative data

Endpoint:
sub-chronic toxicity: dermal
Data waiving:
other justification
Justification for data waiving:
other:
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
In accordance with column 2 of REACH Regulation 1907/2006/EC Annex VIII section 8.6.1 for animal welfare reasons, a repeated dose toxicity study through the dermal route is not required for the following reasons: 1. the substance is classified and labelled as corrosive to the skin: Cat . 1B, H314 according to Regulation (EC) No 1272/2008 (CLP) and R34 according to Directive 67/548/EEC. 2. the physico-chemical and toxicological properties of lithium hydroxide anhydrous and lithiumhydroxide monohydrate suggest no potential for a significant rate of absorption through the skin under non-corrosive conditions (see IUCLID section 7.1.1 and 7.2.3).

Data source

Materials and methods

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion