Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics
Adequacy of study:
other information

Data source

Referenceopen allclose all

Title:
No information
Author:
Johannson FR et al., (1986)|Relationships between toxicity and structure of aliphatic|nitriles. Fund. Appl. Toxicol., 7, pp 690-697.
Title:
No information
Author:
Willhite CC and Smith RP. (1981).|The role of cyanide liberation in the acute toxicity of|Aliphatic nitriles. Toxicol. Appl. Pharmacol., 59(3),|pp589-602.

Materials and methods

Objective of study:
toxicokinetics

Test material

Constituent 1
Chemical structure
Reference substance name:
2-hydroxy-2-methylpropionitrile
EC Number:
200-909-4
EC Name:
2-hydroxy-2-methylpropionitrile
Cas Number:
75-86-5
Molecular formula:
C4H7NO
IUPAC Name:
2-hydroxy-2-methylpropanenitrile

Results and discussion

Applicant's summary and conclusion