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adsorption / desorption: screening
Type of information:
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
See attached QMRF/QPRF
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
Key result
Sample No.:
log Koc
1.7 dimensionless
20 °C
A log Koc value of 1.7 was obtained for the substance using a validated QSAR method. The result is considered to be reliable.

Description of key information


log Koc [(3-chloropropyl)triethoxysilane]: 1.7 (QSAR)


log Koc [ (3-chloropropyl)silanetriol]: 0.45 (calculation)

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

A predicted log Koc value of 1.7 was obtained for (3-chloropropyl)triethoxysilane using a validated QSAR estimation method. The result is considered to be reliable and used for assessment purposes.

The substance hydrolyses moderately rapidly to form (3-chloropropyl)silanetriol and ethanol which have low log Kow values (<3) and thus have low potential for adsorption.

For environmental exposure assessment, adsorption is predicted for the silanol hydrolysis product using the ‘non-hydrophobics’ log Kow-based prediction method for log Koc developed by Sabljic and Güsten (1995) for the European Commission and recommended in EU Guidance.

The relevant equation is:

Log Koc = 0.52 log Kow + 1.02

Therefore, log Koc for silanol hydrolysis product, (3-chloropropyl)silanetriol = 0.45.


Sabljic A and Güsten H (1995). QSARs for soil sorption. in: overview of structure-activity relationships for environmental endpoints. Hermens JLM (ed), report prepared within the framework of the project "QSAR for prediction of fate and effects of chemicals in the environment", an international project of the Environmental Technologies RTD programme (DG XII/D-1) of the European Commission under contract number EV5V-CT92-0211.