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EC number: 224-867-1 | CAS number: 4531-49-1
The test material was subject to a skin irritation test in the rabbit as described in the "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959) of the US Association of Food and Drug Officials (AFDO). Shaved and both intact and scarified skin sites of six rabbits were exposed to 0.5 g test substance in a 50% polyethylene glycol 400 trituration for 24 hours under occlusive conditions. None of the animals showed any skin reactions immediately and 48 hours after the end of exposure. Therefore, the test item has not to be classified for skin irritation according to Regulation (EC) No 1272/2008.
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