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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study under GLP
Remarks:
(as given in OECD SIDS)
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes
Analytical monitoring:
yes
Test organisms (species):
Daphnia magna
Test type:
static
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

- Measured concentration (as mg/L): <1 for control, 930 for the test solution at the beginning of the test; <1 for control, 930 for the test solution at end of the test.
- Statistical results: Not described
- Biological observations 

 Number immobilized as compared to the number exposed: 

Nominal concentration (mg/L)

Measured concentration (mg/L)

Cumulative numbers of immobilized Daphnia (Percent immobility)

 

 

24 h

48 h

Control

-

0 (0)

0 (0)

1000

930 a

0 (0)

0 (0)

 a: geometric mean

Concentration response with 95 % confidence limits: Not described
Cumulative immobilisation: 0 % immobility in control and 1,000 mg/L
Was control response satisfactory (yes/no/unknown): Yes
Reference substance results: 48h-EC50 of potassium bichromate: 0.57 mg/L

 

Conclusions:
There was no inhibition of immobilisation and no abnormal response during the exposure, and 48h-EC50 was greater than 1,000 mg/L of the concentration used.

Description of key information

EC50 (48h) >1000 mg/L for Daphnia magna (OECD TG 202)

Key value for chemical safety assessment

Additional information

Value used for CSA: EC50/LC50 for freshwater invertebrates: >1000 mg/L