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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study under GLP
Remarks:
(as given in OECD SIDS)
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes
Analytical monitoring:
yes
Test organisms (species):
Oryzias latipes
Test type:
semi-static
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC10
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

- Measured concentrations (as mg/L): <0.9 for control, 91.9 for the test solution at the beginning of the test; <0.9 for control, 92.0 for the test solution after 24 h
- Abnormal response: No abnormal responses in the test solution and control during exposure
- Reference substance result: LC50 of copper sulfate pentahydrate at 96 h; 1.5 mg/L.


Nominal concentrations (as mg/L): 0 and 100  
Measured concentrations (as mg/L): 91.9(Day 0)-92.0(Day 1)
Unit [results expressed in what unit]: % survival after 24, 48, 72, 96 h
Element value: 96h-LC50 is above 100 mg/L based on nominal concentration
Statistical results: binomial

- Biological observations: No abnormal response at the test 
concentration and control during the exposure.

- Table showing cumulative mortality 
_____________________________________________________
 Nominal        Measured      Cumulative mortality 
Concentration Concentration            (%) 
 (mg/L)          (mg/L)      24h    48h    72h    96h
Control           <0.9        0      0      0      0
  100           91.9-92.0     0      0     10     10

Conclusions:
96h-LC50 of tris(2-hydroxyethyl) isocyanurate was greater than 100 mg/L and 96h-LC10 of that was 100 mg/L.

Description of key information

LC50 (96h) >100 mg/L for Oryzias latipes (OECD TG 203)

Key value for chemical safety assessment

Additional information

Value used for CSA:LC50 for freshwater fish: > 100 mg/L