Registration Dossier

Toxicological information

Endpoint summary

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Administrative data

Description of key information

An LLNA study was conducted in 2010 (Sanders 2010). This study showed that TPP is a strong skin sensitiser.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

TPP showed positive reactions at test concentrations of 2.5%, 5%, and 10% in a new local lymph node assay (LLNA) (Harlan 2010). The EC3 value from the study was determined to be 1.4%.


Migrated from Short description of key information:
EC3 = 1.4%; TPP is a skin sensitiser.

Justification for classification or non-classification

TPP has been classified as Skin Sens. 1.