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Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer reviewed data base

Data source

Reference
Reference Type:
secondary source
Title:
Effect of N-Monosubstitution on the Basic Properties of Ethylenediamine
Author:
Keller; Edwards
Year:
1952
Bibliographic source:
J. Am. Chem. Soc., 1952, 74 (11), p 2931. cited in Beilstein, Registry No. 506012, 29 Jan 2007

Materials and methods

Test guideline
Guideline:
other: measured
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-aminoethylamino)ethanol
EC Number:
203-867-5
EC Name:
2-(2-aminoethylamino)ethanol
Cas Number:
111-41-1
Molecular formula:
C4H12N2O
IUPAC Name:
2-[(2-aminoethyl)amino]ethan-1-ol
Details on test material:
Name of test material (as cited in study report): 2-(2-aminoethylamino)ethanol
Analytical purity: pure

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
6.83
Temp.:
25 °C
Remarks on result:
other: potentiometric, H2O
No.:
#2
pKa:
9.82
Temp.:
25 °C
Remarks on result:
other: potentiometric, H2O

Applicant's summary and conclusion