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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer reviewed data base

Data source

Reference
Reference Type:
secondary source
Title:
Effect of N-Monosubstitution on the Basic Properties of Ethylenediamine
Author:
Keller; Edwards
Year:
1952
Bibliographic source:
J. Am. Chem. Soc., 1952, 74 (11), p 2931. cited in Beilstein, Registry No. 506012, 29 Jan 2007

Materials and methods

Test guideline
Guideline:
other: measured
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-aminoethylamino)ethanol
EC Number:
203-867-5
EC Name:
2-(2-aminoethylamino)ethanol
Cas Number:
111-41-1
Molecular formula:
C4H12N2O
IUPAC Name:
2-[(2-aminoethyl)amino]ethan-1-ol
Details on test material:
Name of test material (as cited in study report): 2-(2-aminoethylamino)ethanol
Analytical purity: pure

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
6.83
Temp.:
25 °C
Remarks on result:
other: potentiometric, H2O
No.:
#2
pKa:
9.82
Temp.:
25 °C
Remarks on result:
other: potentiometric, H2O

Applicant's summary and conclusion