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Diss Factsheets

Administrative data

Endpoint:
epidemiological data
Type of information:
experimental study
Adequacy of study:
weight of evidence

Data source

Reference
Reference Type:
publication
Title:
Occupational exposure to HI-SIL and SILENE.
Author:
Plunkett ER, DeWitt BJ
Year:
1962
Bibliographic source:
Arch. Environ. Health, 5, 469-472

Materials and methods

Study type:
other: Monitoring at workplace and health check of workers
Endpoint addressed:
repeated dose toxicity: inhalation
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Silicic acid, calcium salt
EC Number:
215-710-8
EC Name:
Silicic acid, calcium salt
Cas Number:
1344-95-2
Molecular formula:
CaSiO3
IUPAC Name:
calcium oxosilanediolate
Details on test material:
Note: The exposure to the target compound overlaps with exposure to a silica that was also produce in that plant:
Hi-Sil (synthetic amorphous silica, precipitated).

- Name of test material (as cited in study report): Silene EF
- Substance type: inorganic
- Physical state: solid; white powder
- Analytical purity:
- Analytical data before ignition: SiO2 (64 %); CaO (18 %); Al2O3 (0.6 %); MgO (0.1 %); NaCl (1.5 %);
- loss at 105 °C: 5 %
- loss on ignition: 15 %
- pH ~10 (5 % water suspension)
- surface area: 80 m2/g

Method

Type of population:
occupational
Ethical approval:
not applicable
Exposure assessment:
measured

Results and discussion

Applicant's summary and conclusion