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EC number: 228-408-6 | CAS number: 6259-76-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption, other
- Remarks:
- other: Calculation adsorption
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 1982
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- This data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained. This handbook is well recognised and reliable.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Handbook of Chemical Property Estimation Methods: Environmental Behavior of Organic Compounds
- Author:
- Lyman, W.J., Rosenblatt, D.H. and Reehl, W.J.
- Year:
- 1 982
- Bibliographic source:
- Handbook of Chemical Property Estimation Methods: Environmental Behavior of Organic Compounds
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- This data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained.
- GLP compliance:
- no
- Remarks:
- not required
- Type of method:
- other: Calculation
- Media:
- other: Calculation
Test material
- Reference substance name:
- Hexyl salicylate
- EC Number:
- 228-408-6
- EC Name:
- Hexyl salicylate
- Cas Number:
- 6259-76-3
- Molecular formula:
- C13H18O3
- IUPAC Name:
- hexyl salicylate
- Details on test material:
- - Name of test material (as cited in study report): Hexyl Salicylate
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not relevant - Radiolabelling:
- no
Study design
- Test temperature:
- Not relevant
HPLC method
- Details on study design: HPLC method:
- Not relevant
Batch equilibrium or other method
- Analytical monitoring:
- not required
- Details on sampling:
- Not relevant
- Details on matrix:
- Not relevant
- Details on test conditions:
- Not relevant
- Computational methods:
- Not relevant
Results and discussion
Adsorption coefficient
- Type:
- Koc
- Value:
- 2 981
Partition coefficients
- Type:
- other: Not relevant QSAR calculation
- Remarks on result:
- other: A quantitative result is not provided for the partition coefficient for adsorption/desorption, since the Koc was predicted via QSAR calculation.
Results: HPLC method
- Details on results (HPLC method):
- Not relevant
Results: Batch equilibrium or other method
- Adsorption and desorption constants:
- Not relevant
- Recovery of test material:
- Not relevant
- Concentration of test substance at end of adsorption equilibration period:
- Not relevant
- Concentration of test substance at end of desorption equilibration period:
- Not relevant
- Transformation products:
- no
- Details on results (Batch equilibrium method):
- Not relevant
- Statistics:
- Not relevant
Any other information on results incl. tables
Table 1: results
Molecular Weight |
Log K(ow) |
Log (l/s) |
l/s (l/mol) |
S (mol/L) |
S (mg/L) |
Log BCF calc. |
BCF |
Bioaccumulation Significant? |
S measured mg/L |
Vp mmHg at 20°C |
VOC defined as vp >0.076 mm Hg |
HLC calc Pa m3/mol |
HLC Quoted/measured Pa m3/mol |
Ex Croner Env |
LogKoc calc |
Koc calc |
Koc quoted/measured |
Interpretation of Koc |
Log Koc calc |
Koc calc |
222 |
5.5 |
5.05 |
1.13E+05 |
8.88E-06 |
2 |
3.95 |
8913 |
Y |
2.0 |
0.01 |
N |
150.1 |
H |
5.15 |
1E+04 |
3.5E+04 (Based on BAC & HCA) |
H |
3.5 |
2981 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- validated method
- Conclusions:
- The Koc for Hexyl salicylate was estimated to be 2981. This means that Hexyl Salicylate has a slight mobility in soil.
- Executive summary:
The Koc for Hexyl salicylate was estimated to be 2981. This suggests that Hexyl Salicylate has a slight mobility in soil.
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