Registration Dossier
Registration Dossier
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EC number: 429-460-4 | CAS number: 7078-98-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Two studies were acute fish toxicity studies have been conducted.
In one study (Ellenberg W & Rielly PD (1999)) the test substanced showed some acute toxicity at the limit of water solubility, however this may have been caused by low oxygen levels.
In the other study (Liu H (1998)) the test substance showed no toxicity at the limit of water solubility in the study.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
Study Reference: Ellenberg W & Rielly PD (1999)
A static freshwater toxicity test was conducted (to OECD guideline 203) to determine the acute toxicity of the water available fraction of the test substance to Rainbow Trout, 0.mykiss, under static renewal conditions. A limit test was initiated with one concentration of test substance (100 mg whole material/L), which was applied to the dilution water and stirred to achieve a stable water available fraction (WAF). The criterion for effect was death.
Mortality of the rainbow trout exposed for 96 hours to the WAF of test substance was 17 percent. Therefore, the 96-hour LC50 was >100 mg wm/L (expressed as loading rate). The no-observed-effect concentration (NOEC) was >100 mg wm/L based on low mortality and/or sublethal effects observed at the test concentration. Based on the reduced levels of dissolved oxygen in the control and treatment chambers, it cannot be stated the fish mortality was solely due to the test substance WAF.
Study Reference: Liu H (1998)
A static-renewal freshwater toxicity test was conducted to determine the acutetoxicity of the test substance to rainbow trout,Oncorhynchus mykiss.The criterion for effect was death.
Nominal concentrations of 1000, 10000 and 100000µg whole material (wm)/L were tested.
The measured concentrations of each test concentration was <3.42µg wm/L.
The 96-hour LC50 was >3.42 µg wm/L. The no-observed-effect concentration (NOEC) was 3.42 µg wm/L based on a lack of mortality and/or sublethal effects observed at all test concentrations.
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