Registration Dossier
Registration Dossier
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EC number: 200-900-5 | CAS number: 75-77-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No data are available for Chlorotrimethylsilane. A 48-hour EC50 of 124 mg/L has however been determined for the effects of a read-across substance, Trimethylsilanol (CAS 1066-40-6), on mobility of Daphnia magna. A NOEC of <60 mg/L has been determined in the same test.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to aquatic invertebrates are available for Chlorotrimethylsilane, However a study of short-term toxicity to Daphnia magna is available for the related substance Trimethylsilanol. Trimethylsilanol (CAS 1066-40-6) is the hydrolysis product of Chlorotrimethylsilane 75-77-4. The hydrolysis half-life of chlorotrimethylsilane (see Section 5.1.2) indicates that, under conditions relevant to the short-term invertebrate toxicity test, hydrolysis to trimethylsilanol and hydrogen chloride will occur over the course of the test. Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media and are discussed in the CSR.
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