Registration Dossier
Registration Dossier
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EC number: 932-231-6 | CAS number: 1335202-81-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A study was conducted using 10 male and 10 female guinea pigs to determine the potential of the analogue substance (NaLAS) to be sensitizing to skin. Animals were given intradermal injections of 25% test solution followed one week later by a second induction done by dermal exposure to 25% test solution for 24 hrs. On day 21, the challenge exposure was performed where all animals were exposed to 12.5% test solution dermally. No positive reactions were observed. The analogue substance is not sensitizing and therefore it not expected that CaDDBS will be a skin sensitiser.
Migrated from Short description of key information:
The CaDDBS analogue substance sodium LAS was tested using the guinea pig sensitisation test. No positive reactions were observed and therefore the analogue substance is not a skin sensitiser. Based on these results CaDDBS is not expected to be a skin sensitiser.
Justification for classification or non-classification
Based on the lack of reactions in a guinea pig skin sensitisation study conducted on the analogue NaLAS, CaDDBS will not be classified under the DSD or CLP.
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