Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 932-231-6 | CAS number: 1335202-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
A skin irritation study was conducted using three female rabbits exposed to 0.5 ml of test substance on the dorsal area of the trunk for four hours and extended observations made for up to 21 days. Mild to moderately severe edema and erythema were noted but were generally reversible by either 7 or 21 days. at the 1, 24, 48, and 72 hr observations. The test substance is therefore classified as a Category 2 skin irritant. Similarly, rabbits were exposed to 0.1 ml of 100% test substance in the eye for 24 hrs. Results show that the test substance may cause serious damage to the eyes which was not reversible and therefore the substance is classified as corrosive.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Three female rabbits were exposed to 0.5 ml of test substance on the dorsal area of the trunk for four hours. After four hours, the test substance was removed by washing with lukewarm water. Observations for erythema and edema were made 0.5-1, 24, 48, and 72 hrs. Since adverse effects were not fully resolved by the 72 hr observation, further observations were made at 7, 14, and 21 days. Mild to moderately severe edema and erythema were noted at the 1, 24, 48, and 72 hr observations. Erythema and edema cleared by the 7 day observation, but the erythema returned by the 14 day observation. This was clearing by the 21 day observation. The test substance is classified as a Category 2 irritant according to EU DSD and CLP guidelines.
Similarly, rabbits were exposed to 0.1 ml of 100% test substance in the eye for 24 hrs. Results show that the test substance may cause serious damage to the eyes.
Effects on skin irritation/corrosion: irritating
Effects on eye irritation: irritating
Justification for classification or non-classification
Based on the results of an in vivo skin irritation study, CaDDBS is classified as R38 according to the DSD and as Category 2 irritant (H315) under the CLP guidelines. In addition, CaDDBS is classified as R41, may cause serious damage to the eyes, under the DSD and Eye damage 1 (H318) under the CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.