Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Study period:
2000
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Bioaccumulation judged by accepted calculation method.

Data source

Reference
Reference Type:
other: calculation
Title:
Unnamed
Year:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: calculated by EPIWIN
Deviations:
no
Principles of method if other than guideline:
Method: other: calculated
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
calculation
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
calculation
Radiolabelling:
no

Test solutions

Vehicle:
no
Details on preparation of test solutions, spiked fish food or sediment:
not applicable

Study design

Test type:
other: not applicable

Test conditions

Hardness:
not applicable
Test temperature:
not applicable
pH:
not applicable
Dissolved oxygen:
not applicable
TOC:
not applicable
Salinity:
not applicable
Details on test conditions:
not applicable
Nominal and measured concentrations:
not applicable
Reference substance (positive control):
not required
Details on estimation of bioconcentration:
Log BCF was calculated with the program EPIWIN. For nonionic substances with a log Kow< 1.0 this program specifies a log BCF = 0.5., which is in accordance with recommendations of the US EPA.

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.16
Basis:
not specified
Calculation basis:
steady state
Details on kinetic parameters:
not applicable
Metabolites:
not applicable
Results with reference substance (positive control):
not applicable
Details on results:
LogKow used: 0.40 log BCF: 0.5
Reported statistics:
not applicable

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
No risk of bioaccumulation for this substance.
Executive summary:

Taking into consideration the measured octanol/water partition coefficients of 0.34 and 0.40 no

potential for bioaccumulation/bioconcentration and geoaccumulation can be identified. Assuming a

log Kow of 0.40 a calculated bioconcentration factor of 3.162 (log BCF = 0.5) results there from

(EPIWIN 2000).