Registration Dossier
Registration Dossier
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EC number: 202-716-0 | CAS number: 98-95-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with slight modifications according to Van Leeuwen et al. (1985). Limited documentation.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 982
- Report date:
- 1982
- Reference Type:
- secondary source
- Title:
- European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3
- Author:
- European Chemicals Bureau
- Year:
- 2 007
- Bibliographic source:
- 3rd Priority List, Volume: 77
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- no
- Remarks:
- test prior to 1 June 2008
Test material
- Reference substance name:
- Nitrobenzene
- EC Number:
- 202-716-0
- EC Name:
- Nitrobenzene
- Cas Number:
- 98-95-3
- Molecular formula:
- C6H5NO2
- IUPAC Name:
- nitrobenzene
- Details on test material:
- - Analytical purity: No data about the degree of purity of the test substance were provided.
DMSO (purity 99%) was used as vehicle for the preparation of the stock solution.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Chlorella pyrenoidosa
- Details on test organisms:
- Growing Chlorella pyrenoidosa
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 18 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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