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Short-term toxicity to fish

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Description of key information

No toxic effects up to the limit of water solubility (< 1 mg/L) for Danio rerio (OECD 203), read-across.

Key value for chemical safety assessment

Additional information

No studies investigating the short-term toxicity of Glycerides, C16-18 mono- (CAS No. 91052-47-0) to fish are available. Therefore, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related category members Glycerides, C14-18 mono- and di- (CAS No. 67701-33-1) was conducted. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance within this category was used.


This GLP-study was conducted according to ISO guideline 7346-1 (Guhl, 1992). Individuals of Danio rerio were exposed for 96 hours to the test substance within a semi-static water regime, at nominal concentrations of 3000 and 10000 mg/L. No mortality was observed at any of the tested concentrations and therefore the LC50 (96 h) was determined to be > 10,000 mg/L (nominal concentration).


Based on the results obtained for the structurally related analogue (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), no acute toxicity of Glycerides, C16-18 mono- (CAS No. 91052-47-0) to fish up to the limit of its water solubility is expected.