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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

There are several OECD 203 guideline GLP studies with nominal test concentrations above 10000 mg/L with Methacrylic acid esters of different alcohol mixtures (C12 - C16). They showed no toxicity to fish.
Therefore, it appears that saturated solutions of the long-chain methacrylate esters are non-toxic to fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
10 000 mg/L

Additional information

Read across to structural analogue substance Isotridecyl methacrylate CAS: 85736-97-6 and Octadecyl methacrylate (CAS: 32360 -05 -7, category member substance):

LC50 [96 h] > 10000 mg / L

There are two guideline / GLP studies available which represent the whole range of long-chain methacrylate esters from C12 to C22.

Concentrations used in the available tests are up to five orders of magnitude above the water solubility of the long-chain methacrylate esters (C12 – C22) which is < 1 µg/l. Therefore, emulsions or even two-layer systems of the esters with water have been tested instead of solutions setting a limitation to the validity of the studies. However, it appears that saturated solutions of the long-chain methacrylate esters are non-toxic to fish. Further acute toxicity to fish studies on long-chain methacrylate esters with limited documentation are confirming these test results.