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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Results of two guideline studies (OECD 209 Activated sludge, respiration Inhibition test) are available. In both studies acetophenone shows no inhibition of activated sludge respiration up to concentrations of 1000 mg/L (3 h IC50>1000 mg/L). Furthermore, a cell multiplication inhibition test (TETRATOX) using Tetrahymena pyriformis is available: 40 h IC50=346 mg/L (nominal).

Key value for chemical safety assessment

EC50 for microorganisms:
346 mg/L

Additional information