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EC number: 205-524-5 | CAS number: 142-16-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
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- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Zebra fish LC50 (96 hrs): >100 mg/l (semi-static, nominal)
Golden orfe LC50 (48 hrs): 86 mg/l (static, nominal)
Golden orfe LC0 (48 hrs): 40 mg/l (static, nominal)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
Three studies are available for bis(ethylhexyl) maleate, assessing the acute toxicity of the substance to fish. The first study was conducted according to OECD 203 using zebra fish as test organism. The exposure period was 96 hours under semi-static conditions, and the test substance concentration was analytically determined after 24 hours. Here, the recovery of the test substance was very low. However, as water accommodated fractions were tested, the EC50 was based on nominal values, resulting in an 96 -hour values of >100 mg/L. Two studies were conducted under static conditions according to the German national DIN standard 38 412, using Golden orfe as test organism. Both tests are limited to an exposure period of only 48 hours, which is too short in comparison to currently valid standards. Furthermore, today Golden orfe is not the standard test organism anymore, as it is a seasonal animal, which leads to higher variations of the test results as in tests conducted with non-seasonal fish like zebra fish. Therefore, the study according to OECD was regarded as the most reliable one and selected as the key study, although the results of both tests with Golden orfe were lower than the one with Zebra fish.
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